{"product_id":"fy-ig0450-50","title":"SMAD7 Mouse mAb(3E3)","description":"\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e WB 1:1,000-2,000  IHC 1:200-500\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous SMAD7proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e SMAD7 MADH7 MADH8\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e SMAD family member 7(SMAD7) Homo sapiens The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding,this complex translocates to the cytoplasm,where it interacts with TGF-beta receptor type-1 (TGFBR1),leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1.\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e WB,IHC\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M,R\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 46KD\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e 46KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e P49841\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0450\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e SMAD7 Mouse mAb(3E3)\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['50', '100']","brand":"Feiyuebio","offers":[{"title":"50","offer_id":50359079338264,"sku":"FY-IG0450-50","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/Feiyuebio_314e5323-a477-47fd-a219-23849800a3a6.png?v=1749884232","url":"https:\/\/danabiosci.com\/products\/fy-ig0450-50","provider":"Dana Bioscience","version":"1.0","type":"link"}