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SKU:FY-IG0450-1
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Name: SMAD7 Mouse mAb(3E3)
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-2,000 IHC 1:200-500
Specificity: Antibody can detect endogenous SMAD7proteins.
Alternative Names: SMAD7 MADH7 MADH8
Background: SMAD family member 7(SMAD7) Homo sapiens The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding,this complex translocates to the cytoplasm,where it interacts with TGF-beta receptor type-1 (TGFBR1),leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1.
Applications: WB,IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 46KD
Protein MW (KDa): 46KD
SWISS: P49841
Source: Mouse
Antigen: Recombinant Protein
Category: Monoclonal
Catalog Number: FY-IG0450
Title: 50/100
Size Raw: IgG1
Size List: ['1']
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-2,000 IHC 1:200-500
Specificity: Antibody can detect endogenous SMAD7proteins.
Alternative Names: SMAD7 MADH7 MADH8
Background: SMAD family member 7(SMAD7) Homo sapiens The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding,this complex translocates to the cytoplasm,where it interacts with TGF-beta receptor type-1 (TGFBR1),leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1.
Applications: WB,IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 46KD
Protein MW (KDa): 46KD
SWISS: P49841
Source: Mouse
Antigen: Recombinant Protein
Category: Monoclonal
Catalog Number: FY-IG0450
Title: 50/100
Size Raw: IgG1
Size List: ['1']
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