{"product_id":"fy-ig0440-1","title":"50\/100","description":"\u003cstrong\u003eName:\u003c\/strong\u003e NFκB p65 Mouse Monoclonal Antibody(5G6)\u003cbr\u003e\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e WB 1:500-2,000  IHC 1:200-500  IF 1:100-200  IP 1:200\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous NFκB p65 proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e NF kappa B p65,NFKB3,p65,p65 NF kB,RELA,TF65,Transcription Factor p65\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e NFkB p65 is ubiquitinated leading to its proteosomal degradation,which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP,enhancing transcriptional activity. NFkB p65 is also acetylated at K122,enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB,which coordinates various aspects of immune function required for resistance to infection.\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e WB,IHC,IF,IP\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M,R\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 65KD\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e 65KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e Q04206\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0440\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e 50\/100\u003cbr\u003e\u003cstrong\u003eSize Raw:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['1']","brand":"Feiyuebio","offers":[{"title":"1","offer_id":50353325474072,"sku":"FY-IG0440-1","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/Feiyuebio_ddd08789-75d9-4b79-9980-74bc8afc5dfb.png?v=1749697398","url":"https:\/\/danabiosci.com\/products\/fy-ig0440-1","provider":"Dana Bioscience","version":"1.0","type":"link"}