{"product_id":"fy-ig0389-1","title":"50\/100","description":"\u003cstrong\u003eName:\u003c\/strong\u003e Claudin-2 Mouse Monoclonal Antibody（8H11）\u003cbr\u003e\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e WB 1:1,000-2,000  IHC 1:100-200\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous Claudin-2 proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e Claudin2,CLDN2,SP82\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e The claudin family is composed of 23 integral membrane proteins,and their expression,which varies among tissue types,may determine both the strength and properties of the epithelial barrier. Alteration in claudin protein expression pattern is associated with several types of cancer . Claudin-2 is expressed primarily in the proximal tubule of the normal mammalian kidney,where it regulates transepithelial ion (e.g.,Na+,Cl-) reabsorption . Increased expression of Claudin-2 has been reported in some cancer cell lines ,including A549 lung adenocarcinoma cells,where its nuclear distribution was positively associated with enhanced proliferation .\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e WB,IHC\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M,R\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 25KD\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e 25KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e P57739\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Synthetic Peptide\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0389\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e 50\/100\u003cbr\u003e\u003cstrong\u003eSize Raw:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['1']","brand":"Feiyuebio","offers":[{"title":"1","offer_id":50353322131736,"sku":"FY-IG0389-1","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/Feiyuebio_16a2c8f8-4a2c-4da1-b111-ddbe66afcf21.png?v=1749697252","url":"https:\/\/danabiosci.com\/products\/fy-ig0389-1","provider":"Dana Bioscience","version":"1.0","type":"link"}