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Feiyuebio
SKU:FY-IG0380-50
HSP70 Mouse Monoclonal Antibody (3G10)
HSP70 Mouse Monoclonal Antibody (3G10)
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Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-2,000 IHC 1:200-500 IF 1:100-200
Specificity: Antibody can detect endogenous HSP70 proteins.
Alternative Names: nan
Background: The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding,and help to protect cells from stress. Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity,such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes,the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues,and interacts with them. This spontaneous interaction is reversible,and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However,the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70,increasing its normally slow rate of ATP hydrolysis.
Applications: WB,IHC,IF
Species Cross-Reactivity: H,M,R,Pg
Molecular Weight: 70KD
Isotype: IgG1
Protein MW （KDa）: 70KD
SWISS: P08107
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0380
Title: HSP70 Mouse Monoclonal Antibody (3G10)
Size List: ['50', '100']
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:1,000-2,000 IHC 1:200-500 IF 1:100-200
Specificity: Antibody can detect endogenous HSP70 proteins.
Alternative Names: nan
Background: The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding,and help to protect cells from stress. Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity,such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes,the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues,and interacts with them. This spontaneous interaction is reversible,and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However,the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70,increasing its normally slow rate of ATP hydrolysis.
Applications: WB,IHC,IF
Species Cross-Reactivity: H,M,R,Pg
Molecular Weight: 70KD
Isotype: IgG1
Protein MW （KDa）: 70KD
SWISS: P08107
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0380
Title: HSP70 Mouse Monoclonal Antibody (3G10)
Size List: ['50', '100']
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