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SKU:FY-IG0256-50
Acetyl NF kB P65（K314 K315) Mouse Monoclonal Antibody(2A11)
Acetyl NF kB P65（K314 K315) Mouse Monoclonal Antibody(2A11)
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Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:100-200
Specificity: Antibody can detect endogenous Acetyl NF kB P65（K314/K315) proteins.
Alternative Names: NF kappa B p65,NFKB3,p65,p65 NF kB,RELA,TF65,Transcription Factor p65
Background: NFkB p65 is ubiquitinated leading to its proteosomal degradation,which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP,enhancing transcriptional activity. NFkB p65 is also acetylated at K122,enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB,which coordinates various aspects of immune function required for resistance to infection.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 65KD
Isotype: IgG1
Protein MW （KDa）: 65KD
SWISS: Q04206
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0256
Title: Acetyl NF kB P65（K314 K315) Mouse Monoclonal Antibody(2A11)
Size List: ['50', '100']
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:100-200
Specificity: Antibody can detect endogenous Acetyl NF kB P65（K314/K315) proteins.
Alternative Names: NF kappa B p65,NFKB3,p65,p65 NF kB,RELA,TF65,Transcription Factor p65
Background: NFkB p65 is ubiquitinated leading to its proteosomal degradation,which is required for termination of the NFkB response. Phosphorylation of NFkB p65 on S536 stimulates acetylation of K310 by CBP,enhancing transcriptional activity. NFkB p65 is also acetylated at K122,enhancing DNA binding and impairing the interaction with NFKBIA. The protein is deacetylated by HDAC3. Invasion of a host by a pathogen is frequently associated with the activation of NF-kB,which coordinates various aspects of immune function required for resistance to infection.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 65KD
Isotype: IgG1
Protein MW （KDa）: 65KD
SWISS: Q04206
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0256
Title: Acetyl NF kB P65（K314 K315) Mouse Monoclonal Antibody(2A11)
Size List: ['50', '100']
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