{"product_id":"fy-ig0159-50","title":"CD10 Rabbit Polyclonal Antibody（CD10）","description":"\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e IHC 1:200-500\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous CD10 proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e CALLA,Enkephalinase,MME,NEP,Neutral endopeptidase antibody\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e CD10 is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides,most notably the amyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimer's disease. Synthesized as a membrane-bound protein,the neprilysin ectodomain is released into the extracellular domain after it has been transported from the Golgi apparatus to the cell surface. In neurons,neprilysin is regulated by the protein nicastrin,a component of the gamma secretase complex that performs a necessary step in processing amyloid precursor protein to amyloid beta.\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e IHC\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M,R\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 85KD\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e 85KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e P08473\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0159\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e CD10 Rabbit Polyclonal Antibody（CD10）\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['50', '100']","brand":"Feiyuebio","offers":[{"title":"50","offer_id":50359038837016,"sku":"FY-IG0159-50","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/Feiyuebio_a4373767-9246-4b04-9e79-e6db2750de7e.png?v=1749882637","url":"https:\/\/danabiosci.com\/products\/fy-ig0159-50","provider":"Dana Bioscience","version":"1.0","type":"link"}