{"product_id":"fy-ig0130-50","title":"CK16 Mouse Monoclonal Antibody (6F6)","description":"\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e IHC 1:200\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous CK16 proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e nan\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e Keratin 16 is expressed in keratinocytes,which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly,a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins,but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation,and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e IHC\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M,R\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 51KD\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e 51KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e P08779\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Synthetic Peptide\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0130\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e CK16 Mouse Monoclonal Antibody (6F6)\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['50', '100']","brand":"Feiyuebio","offers":[{"title":"50","offer_id":50359036150040,"sku":"FY-IG0130-50","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/Feiyuebio_da974983-b853-4ecf-ae47-6c999c654c52.png?v=1749882477","url":"https:\/\/danabiosci.com\/products\/fy-ig0130-50","provider":"Dana Bioscience","version":"1.0","type":"link"}