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SKU:FY-IG0130-1
50/100
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Name: CK16 Mouse Monoclonal Antibody (6F6)
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:200
Specificity: Antibody can detect endogenous CK16 proteins.
Alternative Names: nan
Background: Keratin 16 is expressed in keratinocytes,which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly,a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins,but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation,and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 51KD
Protein MW （KDa）: 51KD
SWISS: P08779
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0130
Title: 50/100
Size Raw: IgG1
Size List: ['1']
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: IHC 1:200
Specificity: Antibody can detect endogenous CK16 proteins.
Alternative Names: nan
Background: Keratin 16 is expressed in keratinocytes,which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation-related keratins). Keratin 16 is absent in normal breast tissue and in noninvasive breast carcinomas. Only 10% of the invasive breast carcinomas show diffuse or focal positivity. Reportedly,a relatively high concordance was found between the carcinomas immunostaining with the basal cell and the hyperproliferation-related keratins,but not between these markers and the proliferation marker Ki-67. This supports the conclusion that basal cells in breast cancer may show extensive proliferation,and that absence of Ki-67 staining does not mean that (tumor) cells are not proliferating.
Applications: IHC
Species Cross-Reactivity: H,M,R
Molecular Weight: 51KD
Protein MW （KDa）: 51KD
SWISS: P08779
Source: Mouse
Antigen: Synthetic Peptide
Category: Monoclonal
Catalog Number: FY-IG0130
Title: 50/100
Size Raw: IgG1
Size List: ['1']
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