{"product_id":"fy-ig0097-100","title":"Cofilin 1 Rabbit Polyclonal Antibody(CFL1)","description":"\u003cstrong\u003eCondition:\u003c\/strong\u003e 1mg\/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.\u003cbr\u003e\u003cstrong\u003eStore at:\u003c\/strong\u003e Store at -20°C. Stable for one year from the date of shipment.\u003cbr\u003e\u003cstrong\u003eRecommended dilutions:\u003c\/strong\u003e WB 1:2,000-5,000\u003cbr\u003e\u003cstrong\u003eSpecificity:\u003c\/strong\u003e Antibody can detect endogenous Cofilin proteins.\u003cbr\u003e\u003cstrong\u003eAlternative Names:\u003c\/strong\u003e CFL1,CFL,Cofilin-1,18 KD a phosphoprotein,p18,Cofilin,non-muscle isoform\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e Cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.\u003cbr\u003e\u003cstrong\u003eApplications:\u003c\/strong\u003e WB\u003cbr\u003e\u003cstrong\u003eSpecies Cross-Reactivity:\u003c\/strong\u003e H,M,R\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 19KD\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eProtein MW    （KDa）:\u003c\/strong\u003e ~19KD\u003cbr\u003e\u003cstrong\u003eSWISS:\u003c\/strong\u003e P23528\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eAntigen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eCategory:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eCatalog Number:\u003c\/strong\u003e FY-IG0097\u003cbr\u003e\u003cstrong\u003eTitle:\u003c\/strong\u003e Cofilin 1 Rabbit Polyclonal Antibody(CFL1)\u003cbr\u003e\u003cstrong\u003eSize List:\u003c\/strong\u003e ['50', '100']","brand":"Feiyuebio","offers":[{"title":"100","offer_id":50359030448408,"sku":"FY-IG0097-100","price":0.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/Feiyuebio_d4fb45bf-e3eb-485b-91c3-9b7123c0b3ad.png?v=1749882284","url":"https:\/\/danabiosci.com\/products\/fy-ig0097-100","provider":"Dana Bioscience","version":"1.0","type":"link"}