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SKU:FY-IG0033-1
50/100
50/100
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Name: NF κB P50 Mouse Monoclonal Antibody(5D2)
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:500-1,000
Specificity: Antibody can detect endogenous NF κB P50 proteins.
Alternative Names: NFKB1,nuclear factor nf-kappa-b p105,DNA-binding factor KBF1
Background: Nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines,oxidant-free radicals,ultraviolet irradiation,and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.
Applications: WB
Species Cross-Reactivity: H
Molecular Weight: 50KD
Protein MW （KDa）: 50KD
SWISS: P19838
Source: Mouse
Antigen: Recombinant Protein
Category: Monoclonal
Catalog Number: FY-IG0033
Title: 50/100
Size Raw: IgG1
Size List: ['1']
Condition: 1mg/ml in PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol.
Store at: Store at -20°C. Stable for one year from the date of shipment.
Recommended dilutions: WB 1:500-1,000
Specificity: Antibody can detect endogenous NF κB P50 proteins.
Alternative Names: NFKB1,nuclear factor nf-kappa-b p105,DNA-binding factor KBF1
Background: Nuclear factor kappa B subunit 1(NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines,oxidant-free radicals,ultraviolet irradiation,and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.
Applications: WB
Species Cross-Reactivity: H
Molecular Weight: 50KD
Protein MW （KDa）: 50KD
SWISS: P19838
Source: Mouse
Antigen: Recombinant Protein
Category: Monoclonal
Catalog Number: FY-IG0033
Title: 50/100
Size Raw: IgG1
Size List: ['1']
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