{"product_id":"frizzled-8-polyclonal-antibody-abcb02203","title":"Frizzled-8 Polyclonal Antibody","description":"\u003ch4\u003eAb type\u003c\/h4\u003e\u003cp\u003ePrimary antibody\u003c\/p\u003e\u003ch4\u003eBackground\u003c\/h4\u003e\u003cp\u003eThis intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.\u003c\/p\u003e\u003ch4\u003eReactivity\u003c\/h4\u003e\u003cp\u003eHuman;Mouse;Rat\u003c\/p\u003e\u003ch4\u003eClonality\u003c\/h4\u003e\u003cp\u003ePolyclonal\u003c\/p\u003e\u003ch4\u003eHost\u003c\/h4\u003e\u003cp\u003eRabbit\u003c\/p\u003e\u003ch4\u003eIsotype\u003c\/h4\u003e\u003cp\u003eIgG\u003c\/p\u003e\u003ch4\u003eImmunogen\u003c\/h4\u003e\u003cp\u003eThe antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535\u003c\/p\u003e\u003ch4\u003eStorage Stability\u003c\/h4\u003e\u003cp\u003e-20°C for one year\u003c\/p\u003e\u003ch4\u003eConcentration\u003c\/h4\u003e\u003cp\u003e1 mg\/ml\u003c\/p\u003e\u003ch4\u003eMolecularWeight_Da\u003c\/h4\u003e\u003cp\u003e73300\u003c\/p\u003e\u003ch4\u003esynonyms\u003c\/h4\u003e\u003cp\u003eFZD8; Frizzled-8; Fz-8; hFz8\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"100ul \/ Rabbit \/ Primary antibody","offer_id":42404155097322,"sku":"ABCB02203","price":275.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/758-7580448_monoclonal-antibody-png-transparent-png_2ef3b37e-bde8-45f2-8b2e-dcf957b149af.png?v=1645214835","url":"https:\/\/danabiosci.com\/products\/frizzled-8-polyclonal-antibody-abcb02203","provider":"Dana Bioscience","version":"1.0","type":"link"}