{"product_id":"f54703-0-08ml","title":"CSEN Antibody \/ Calsenilin \/ KCNIP3","description":"\u003cp\u003eKChIP3 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease. Due to utilization of an alternate in-frame translation start codon, the gene for this protein encodes two isoforms with different sizes.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.08 ml \/ Rabbit","offer_id":49477076222232,"sku":"F54703-0.08ML","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_a7fbbb0d-a0f7-4a17-9229-fb5ea1f67a12.jpg?v=1734489499","url":"https:\/\/danabiosci.com\/products\/f54703-0-08ml","provider":"Dana Bioscience","version":"1.0","type":"link"}