{"product_id":"f54392-0-08ml","title":"p21 Antibody \/ CDKN1A","description":"\u003cp\u003eMay be the important intermediate by which p53\/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin- dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D- CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.08 ml \/ Rabbit","offer_id":49477134778648,"sku":"F54392-0.08ML","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_c46624f0-4f48-4402-9224-3905169164f0.jpg?v=1734491555","url":"https:\/\/danabiosci.com\/products\/f54392-0-08ml","provider":"Dana Bioscience","version":"1.0","type":"link"}