{"product_id":"f54382-0-4ml","title":"Exportin 2 antibody \/ CSE1L","description":"\u003cp\u003eProteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha\/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477136384280,"sku":"F54382-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0dfb172a-6a80-440a-8df1-52b0b2b7fa45.jpg?v=1734491607","url":"https:\/\/danabiosci.com\/products\/f54382-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}