{"product_id":"f54127-0-2ml","title":"ERAB Antibody \/ HSD17B10 (N-Terminal Region)","description":"\u003cp\u003eERAB \/ HSD17B10 functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1\/TRMT10C, MRPP2\/HSD17B10 and MRPP3\/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.2 ml \/ Rabbit","offer_id":49477218992408,"sku":"F54127-0.2ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_820d4388-e552-428f-83b3-d0a08d02775c.jpg?v=1734492996","url":"https:\/\/danabiosci.com\/products\/f54127-0-2ml","provider":"Dana Bioscience","version":"1.0","type":"link"}