{"product_id":"f54060-0-1ml","title":"LC3A\/B Antibody","description":"LC3A:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP\/GATE-16 subfamily is essential for a later stage in autophagosome maturation. [UniProt]\u003cp\u003eLC3B:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP\/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.1 ml \/ Mouse","offer_id":49477237211416,"sku":"F54060-0.1ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0ef9478c-610b-4cf8-ae4d-62c75c84e8b1.jpg?v=1734493412","url":"https:\/\/danabiosci.com\/products\/f54060-0-1ml","provider":"Dana Bioscience","version":"1.0","type":"link"}