{"product_id":"f53896-0-05ml","title":"LARGE Antibody \/ Like acetylglucosaminyltransferase","description":"\u003cp\u003eBifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine- beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1). Phosphorylated O- mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1\/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.05 ml \/ Rabbit","offer_id":49477281153304,"sku":"F53896-0.05ML","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_827527ff-68ae-40d4-a7fc-82d670d76418.jpg?v=1734494215","url":"https:\/\/danabiosci.com\/products\/f53896-0-05ml","provider":"Dana Bioscience","version":"1.0","type":"link"}