{"product_id":"f53422-0-4ml","title":"HES1 Antibody","description":"\u003cp\u003eTranscriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477323489560,"sku":"F53422-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_0f136dd4-dd0c-485b-91a4-39fba52dd961.jpg?v=1734495065","url":"https:\/\/danabiosci.com\/products\/f53422-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}