{"product_id":"f53267-0-4ml","title":"FBXW7 Antibody","description":"\u003cp\u003eSubstrate recognition component of an SCF (SKP1-CUL1-F- box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds phosphorylated sites\/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination. Identified substrates include cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477333254424,"sku":"F53267-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_65bc88d1-7150-45e2-80ad-29f22e251950.jpg?v=1734495340","url":"https:\/\/danabiosci.com\/products\/f53267-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}