{"product_id":"f53121-0-4ml","title":"DKK1 Antibody","description":"\u003cp\u003eAntagonizes canonical Wnt signaling by inhibiting LRP5\/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5\/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477343445272,"sku":"F53121-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_16240607-59ca-4afc-b2ea-721eca6aa873.jpg?v=1734495636","url":"https:\/\/danabiosci.com\/products\/f53121-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}