{"product_id":"f52486-0-4ml","title":"SP1 Antibody","description":"\u003cp\u003eSpecificity Protein 1\/SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Mouse","offer_id":49477462262040,"sku":"F52486-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_f11c837b-dead-466a-bd00-65731b4ee5ee.jpg?v=1734496569","url":"https:\/\/danabiosci.com\/products\/f52486-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}