{"product_id":"f52478-0-4ml","title":"STAT3 Antibody","description":"\u003cp\u003eSignal transducer and transcription activator that mediates cellular responses to interleukins, KITLG\/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2\/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Mouse","offer_id":49477463179544,"sku":"F52478-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_be0a57f2-47b5-4437-8507-8dfb8cec96a6.jpg?v=1734496580","url":"https:\/\/danabiosci.com\/products\/f52478-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}