{"product_id":"f52199-0-4ml","title":"p21 Antibody","description":"\u003cp\u003eMay be the important intermediate by which p53\/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex (By similarity).\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477500141848,"sku":"F52199-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_278838e4-e99c-4904-9613-c026f823c64c.jpg?v=1734496925","url":"https:\/\/danabiosci.com\/products\/f52199-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}