{"product_id":"f50892-0-4ml","title":"PAK3 Antibody","description":"\u003cp\u003ePAK3, a member of the STE20 subfamily of Ser\/Thr protein kinases, acts on a variety of targets. PAK3 interacts tightly with GTP-bound but not GDP-bound CDC42\/p21 and RAC1. It shows highly specific binding to the SH3 domains of phospholipase C-gamma and of adapter protein NCK. This protein is highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. PAK3 is autophosphorylated when activated by CDC42\/p21. Defects in PAK3 are the cause of non-specific X-linked nonsyndromic mental retardation type 30 (MRX30). The protein structure contains 1 CRIB domain.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477746426136,"sku":"F50892-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_c8ed2304-a0b8-447d-b214-16d22057d4a9.jpg?v=1734498139","url":"https:\/\/danabiosci.com\/products\/f50892-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}