{"product_id":"f50542-0-4ml","title":"E2F1 Antibody","description":"\u003cp\u003eE2F1 is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1\/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53\/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA binding to its target gene promoters. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477798232344,"sku":"F50542-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_1dc08180-7b75-4576-9a61-8778efa3b2ee.jpg?v=1734499043","url":"https:\/\/danabiosci.com\/products\/f50542-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}