{"product_id":"f49135-0-4ml","title":"SMAD6 Antibody","description":"\u003cp\u003eSMAD6 acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477840961816,"sku":"F49135-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_484a94e6-014b-49e3-b1b6-8317e80d722b.jpg?v=1734500926","url":"https:\/\/danabiosci.com\/products\/f49135-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}