{"product_id":"f48476-0-4ml","title":"Phospho-FAS Antibody (pY291)","description":"\u003cp\u003eReceptor for TNFSF6\/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [UniProt]\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477879300376,"sku":"F48476-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_9abf7b77-dac2-4f42-8163-7d1f9a8c68ac.jpg?v=1734502050","url":"https:\/\/danabiosci.com\/products\/f48476-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}