{"product_id":"f48010-0-4ml","title":"p62 Antibody","description":"\u003cp\u003eSQSTM1\/p62 is an adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. This protein may play a role in titin\/TTN downstream signaling in muscle cells, and may also regulate signaling cascades through ubiquitination. This protein is involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels. SQSTM1\/p62 also appears to play a role in macroautophagic removal of intracellular protein aggregates. Cellular depletion studies of SQSTM1\/p62 have indicated a role for association with LC3 and aggregate proteins in order to facilitate normal formation of the autophagosome.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477897126168,"sku":"F48010-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_133755a4-ac05-449d-9fe2-bee72e0e8bea.jpg?v=1734502744","url":"https:\/\/danabiosci.com\/products\/f48010-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}