{"product_id":"f47999-0-4ml","title":"Mib1 Antibody","description":"\u003cp\u003eMIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477897191704,"sku":"F47999-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_c45d7763-c469-4436-b0c2-4f28f1c12250.jpg?v=1734502750","url":"https:\/\/danabiosci.com\/products\/f47999-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}