{"product_id":"f47999-0-08ml","title":"Mib1 Antibody (Mindbomb)","description":"\u003cp\u003eMIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.08 ml \/ Rabbit","offer_id":49477897224472,"sku":"F47999-0.08ML","price":199.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_7fc98470-8ab9-44f8-b7ef-082424829180.jpg?v=1734502753","url":"https:\/\/danabiosci.com\/products\/f47999-0-08ml","provider":"Dana Bioscience","version":"1.0","type":"link"}