{"product_id":"f45532-0-4ml","title":"Tbk1 Antibody","description":"\u003cp\u003eSerine\/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES\/CCL5 and interferon-beta\/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha\/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.\u003c\/p\u003e","brand":"NSJ Bioreagents","offers":[{"title":"0.4 ml \/ Rabbit","offer_id":49477941526808,"sku":"F45532-0.4ML","price":429.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/get_image_42493927-069b-43c7-a531-9b49d3804c65.jpg?v=1734504388","url":"https:\/\/danabiosci.com\/products\/f45532-0-4ml","provider":"Dana Bioscience","version":"1.0","type":"link"}