{"product_id":"es8699","title":"DC-LAMP rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB;IHC;IF;ELISA\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human;Rat;Mouse;\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic peptide from human protein at AA range: 261-310\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 44kD\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 27074\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e Q9UQV4\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Cell surface . Lysosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle membrane ; Single-pass type I membrane protein . Early endosome membrane ; Single-pass type I membrane protein . During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752). Detected on lysosomes in mature dendritic cells (PubMed:9768752). .\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e Lysosome-associated membrane glycoprotein 3 (LAMP-3;Lysosomal-associated membrane protein 3;DC-lysosome-associated membrane glycoprotein;DC LAMP;Protein TSC403;CD antigen CD208)\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis et al., 1998 [PubMed 9768752]).[supplied by OMIM, Dec 2010],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411628003608,"sku":"ES8699","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES8699-c-1.jpg?v=1751093298","url":"https:\/\/danabiosci.com\/products\/es8699","provider":"Dana Bioscience","version":"1.0","type":"link"}