{"product_id":"es8673","title":"CD11b rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e IHC;IF;mult-IHC;ELISA\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human;Rat;Mouse;\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e IHC-p 1:50-200, ELISA 1:10000-20000\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic peptide from human protein at AA range: 280-360\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 3684\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P11215\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein .\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e Integrin alpha-M (CD11 antigen-like family member B;CR-3 alpha chain;Cell surface glycoprotein MAC-1 subunit alpha;Leukocyte adhesion receptor MO1;Neutrophil adherence receptor;CD antigen CD11b)\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e integrin subunit alpha M(ITGAM) Homo sapiens    This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411621908760,"sku":"ES8673","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES8673-c-1.jpg?v=1751093201","url":"https:\/\/danabiosci.com\/products\/es8673","provider":"Dana Bioscience","version":"1.0","type":"link"}