{"product_id":"es8670","title":"CIS rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e IHC;IF;ELISA\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human;Mouse;Rat\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e IHC-p 1:50-200, ELISA 1:10000-20000\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic peptide from human protein at AA range: 30-90\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 1154\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e Q9NSE2\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e cytoplasm,cytosol,plasma membrane,\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e Cytokine-inducible SH2-containing protein (CIS;CIS-1;Protein G18;Suppressor of cytokine signaling;SOCS)\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e cytokine inducible SH2 containing protein(CISH) Homo sapiens    The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411620827416,"sku":"ES8670","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES8670-c-1.jpg?v=1751093185","url":"https:\/\/danabiosci.com\/products\/es8670","provider":"Dana Bioscience","version":"1.0","type":"link"}