{"product_id":"es4221","title":"SAMHD1 rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB;IHC;IF;ELISA\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human;Rat;Mouse;\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e Western Blot: 1\/500 - 1\/2000. IHC-p: 1\/100-1\/300.  ELISA: 1\/20000. Not yet tested in other applications.\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e The antiserum was produced against synthesized peptide derived from the Internal region of human SAMHD1. AA range:431-480\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 72kD\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 25939\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e Q9Y3Z3\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Nucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. .\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e SAMHD1; MOP5; SAM domain and HD domain-containing protein 1; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1(SAMHD1) Homo sapiens    This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411333845272,"sku":"ES4221","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES4221-c-1.jpg?v=1751080468","url":"https:\/\/danabiosci.com\/products\/es4221","provider":"Dana Bioscience","version":"1.0","type":"link"}