{"product_id":"es2917","title":"NEIL3 rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB;IHC;IF;ELISA\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human;Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e Western Blot: 1\/500 - 1\/2000. Immunohistochemistry: 1\/100 - 1\/300. ELISA: 1\/40000. Not yet tested in other applications.\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e The antiserum was produced against synthesized peptide derived from human NEIL3. AA range:491-540\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 35kD\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 55247\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e Q8TAT5\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Nucleus . Chromosome . Recruited to replication stress sites via interaction with ubiquitinated CMG helicase. .\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e NEIL3; Endonuclease 8-like 3; DNA glycosylase FPG2; DNA glycosylase\/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg\/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411235639576,"sku":"ES2917","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES2917-c-1.jpg?v=1751076059","url":"https:\/\/danabiosci.com\/products\/es2917","provider":"Dana Bioscience","version":"1.0","type":"link"}