ELK Biotechnology

SKU:ES20134

Tubulin α (Acetyl Lys163) rabbit pAb

Tubulin α (Acetyl Lys163) rabbit pAb

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Size
Applications: WB; ELISA
Reactivity: Human;Mouse;Rat
Source: Rabbit
Dilution: WB 1:1000-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human Tubulin α (Acetyl Lys163)
Storage_stability: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed_band(KD): 50kD
Human_gene_id: 7846
Human_swiss_prot_no: Q71U36/P68363/Q9BQE3/Q13748/P68366
Subcellular_location: Cytoplasm, cytoskeleton.
Other_name: Tubulin alpha-1A chain (Alpha-tubulin 3;Tubulin B-alpha-1;Tubulin alpha-3 chain)
Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
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