{"product_id":"es20045","title":"PROC (light chain, Cleaved-Leu179) rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB;ELISA;IHC\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human;Rat;Mouse;\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthesized peptide derived from human PROC (light chain, Cleaved-Leu179)\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 17 45kD\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 5624\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P04070\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Secreted . Golgi apparatus . Endoplasmic reticulum .\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e Vitamin K-dependent protein C (EC 3.4.21.69;Anticoagulant protein C;Autoprothrombin IIA;Blood coagulation factor XIV) [Cleaved into: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide]\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50413659062552,"sku":"ES20045","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES20045-c-1.jpg?v=1751157616","url":"https:\/\/danabiosci.com\/products\/es20045","provider":"Dana Bioscience","version":"1.0","type":"link"}