{"product_id":"es1746","title":"Bak rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB;IHC;IF;ELISA\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human;Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e Western Blot: 1\/500 - 1\/2000. IHC-p: 1:100-300 ELISA: 1\/20000. IF 1:100-300 Not yet tested in other applications.\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e The antiserum was produced against synthesized peptide derived from human Bak. AA range:1-50\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 25kD\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 578\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e Q16611\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Mitochondrion outer membrane ; Single-pass membrane protein .\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e BAK1; BAK; BCL2L7; CDN1; Bcl-2 homologous antagonist\/killer; Apoptosis regulator BAK; Bcl-2-like protein 7; Bcl2-L-7\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411143856408,"sku":"ES1746","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES1746-c-1.jpg?v=1751071992","url":"https:\/\/danabiosci.com\/products\/es1746","provider":"Dana Bioscience","version":"1.0","type":"link"}