{"product_id":"es16916","title":"DOCK4 rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human; Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1：500-2000\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthesized peptide derived from human DOCK4 AA range: 533-583\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e -20°C\/1 year\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1 mg\/ml\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 9732\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e Q8N1I0\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Cell membrane . Cell projection . Cytoplasm, cytosol . Colocalizes with EPHA2, RHOG and CTTN\/cortactin at the tip of protrusions in migrating cells. .\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized. [provided by RefSeq, Jul 2008],","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50413506068760,"sku":"ES16916","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/ES16916-c-1.jpg?v=1751152444","url":"https:\/\/danabiosci.com\/products\/es16916","provider":"Dana Bioscience","version":"1.0","type":"link"}