{"product_id":"em1087","title":"Histone H3 (di methyl K79) Mouse mAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB, IHC\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human, Rat, Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1:500-2,000   IHC 1:200-500\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic Peptide\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 15kDa\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 8290\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P68431\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Nucleus,Chromosome\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e H3 histone antibody, HIST1H3A antibody, Histone cluster 1, H3a antibody\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411031101720,"sku":"EM1087","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EM1087-c-1.jpg?v=1751069005","url":"https:\/\/danabiosci.com\/products\/em1087","provider":"Dana Bioscience","version":"1.0","type":"link"}