{"product_id":"em1076","title":"CA IX\/Carbonic Anhydrase IX Mouse mAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB, IHC, IP\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1:3,000 IP 1:200  IHC 1:100-200\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic Peptide\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 35-38kDa\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 768\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e Q16790\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane.\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54\/58N, pMW1, RCC associated antigen G250\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411030741272,"sku":"EM1076","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EM1076-c-1.jpg?v=1751068957","url":"https:\/\/danabiosci.com\/products\/em1076","provider":"Dana Bioscience","version":"1.0","type":"link"}