{"product_id":"em1071","title":"CD5 Mouse mAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e IHC\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human, Rat, Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e IHC 1:100-200\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic Peptide\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 921\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P06127\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Membrane\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e CD5 molecule, LEU1, Lymphocyte antigen T1\/Leu 1, T1\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e CD5 is a cluster of differentiation found on a subset of IgM-secreting B cells called B-1 cells, and also on T cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli (such as bacterial proteins) and not by normal tissue proteins.","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411029725464,"sku":"EM1071","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EM1071-c-1.jpg?v=1751068941","url":"https:\/\/danabiosci.com\/products\/em1071","provider":"Dana Bioscience","version":"1.0","type":"link"}