{"product_id":"em1058","title":"Myosin Heavy Chain Mouse mAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e IHC, IF\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human, Mouse, Rat, Fruit Fly, Nematode\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e IHC 1:200 IF 1:100\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic Peptide\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 220kDa\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 4619\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P12882\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Cytoplasm, Thick filament\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e Bsh, CG17927, Dm II, Dmel\\CG17927, DmMHC, DROMHC, DroMII, FBgn0002741, Ifm(2)2, l(2)36Ae, l(2)k10423, l(2)M66, Mhc, Mhc36B, mMHC, MRP, Myo, Myosin heavy chain, Nup, Sht, sMHC, Stp\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411026612504,"sku":"EM1058","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EM1058-c-1.jpg?v=1751068887","url":"https:\/\/danabiosci.com\/products\/em1058","provider":"Dana Bioscience","version":"1.0","type":"link"}