{"product_id":"em1030","title":"PCNA Mouse mAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB, IHC\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human, Rat, Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Mouse\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1:5,000 IHC 1:200\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Synthetic Peptide\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Monoclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG1\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 29kDa\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 5111\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P12004\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Nucleus\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411022680344,"sku":"EM1030","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EM1030-c-1.jpg?v=1751068770","url":"https:\/\/danabiosci.com\/products\/em1030","provider":"Dana Bioscience","version":"1.0","type":"link"}