{"product_id":"elisa-kit-for-hepcidin-hepc-abcc24941","title":"ELISA Kit for Hepcidin (Hepc)","description":"\u003ch4\u003eFormat\u003c\/h4\u003e\u003cp\u003e48T, \u003ci\u003e96T\u003c\/i\u003e, 96T×5, 96T×10, 96T×100\u003c\/p\u003e\u003ch4\u003eDetection range\u003c\/h4\u003e\u003cp\u003e320-200,000pg\/mL\u003c\/p\u003e\u003ch4\u003eApplication\u003c\/h4\u003e\u003cp\u003eEnzyme-linked immunosorbent assay for Antigen Detection.\u003c\/p\u003e\u003ch4\u003eOrganism species\u003c\/h4\u003e\u003cp\u003eHomo sapiens (Human)\u003c\/p\u003e\u003ch4\u003eSensitivity\u003c\/h4\u003e\u003cp\u003eThe minimum detectable dose of this kit is typically less than 112pg\/mL\u003c\/p\u003e\u003ch4\u003eSample type\u003c\/h4\u003e\u003cp\u003eSerum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids\u003c\/p\u003e\u003ch4\u003eAssay length\u003c\/h4\u003e\u003cp\u003e2h\u003c\/p\u003e\u003ch4\u003eMethod\u003c\/h4\u003e\u003cp\u003eCompetitive Inhibition\u003c\/p\u003e\u003ch4\u003eTest principle\u003c\/h4\u003e\u003cp\u003eThis assay employs the competitive inhibition enzyme immunoassay technique. A monoclonal antibody specific to Hepcidin (Hepc) has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled Hepcidin (Hepc) and unlabeled Hepcidin (Hepc) (Standards or samples) with the pre-coated antibody specific to Hepcidin (Hepc). After incubation the unbound conjugate is washed off. Next, avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. The amount of bound HRP conjugate is reverse proportional to the concentration of Hepcidin (Hepc) in the sample. After addition of the substrate solution, the intensity of color developed is reverse proportional to the concentration of Hepcidin (Hepc) in the sample.\u003c\/p\u003e\u003ch4\u003eAlternative Names\u003c\/h4\u003e\u003cp\u003eHAMP; HFE2B; PLTR; LEAP1; Hepcidin Antimicrobial Peptide; Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor\u003c\/p\u003e\u003ch4\u003eItem Name\u003c\/h4\u003e\u003cp\u003eHepcidin\u003c\/p\u003e\u003ch4\u003eResearch Area\u003c\/h4\u003e\u003cp\u003eMetabolic pathway;Endocrinology;Hematology;Genetic science;\u003c\/p\u003e\u003ch4\u003eReference\u003c\/h4\u003e\u003cp\u003e\u003ca href=\"http:\/\/link.springer.com\/article\/10.1134\/S1819712414030040\"\u003eSerum iron metabolism markers including hepcidin in multiple sclerosis patients\u003c\/a\u003e;\u003ca href=\"http:\/\/mis.zu.edu.eg\/ajied\/Ajied_System_Files\/Attach114_1.pdf\"\u003eMonitoring Hepcidin Level in Chronic Hepatitis C Virus Patients during Therapy\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25193892\"\u003eHepcidin and regulation of iron homeostasis in maintenance hemodialysis patients\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25245337\"\u003eThe interplay among iron metabolism, endothelium \nand inflammatory cascade in dysmetabolic disorders\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25628652\"\u003eAn Evaluation of the Correlation between Hepcidin Serum Levels and Disease Activity in Inflammatory Bowel Disease\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25651734\"\u003eSerum hepcidin levels in Bulgarian population.\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25742771\"\u003eLiver Congestion in Heart Failure Contributes to Inappropriately Increased Serum Hepcidin despite Anemia\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/25858146\"\u003eHepcidin regulation in prostate and its disruption in prostate cancer\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26536083\"\u003eEffect of a More Permeable Dialysis Membrane on ESA Resistance in Hemodialysis Patients - A Pilot Investigation\u003c\/a\u003e;\u003ca href=\"http:\/\/search.proquest.com\/openview\/e01ad7c4a9109ed5fadb03ec206d7bdc\/1?pq-origsite=gscholar\"\u003eUrinary Hepcidin in Diagnosis of Iron Deficiency Anemia\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24954786\"\u003eHepcidin in tumor‐related iron deficiency anemia and tumor‐related anemia of chronic disease: pathogenic mechanisms and diagnosis\u003c\/a\u003e;\u003ca href=\"http:\/\/www.scirp.org\/journal\/PaperInformation.aspx?paperID=59107\"\u003eThe Effects of Treatment on Serum Hepcidin and Iron Homeostasis in HIV-1-Infected In-dividuals\u003c\/a\u003e;\u003ca href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26154696\"\u003eHydrogen sulfide attenuates inflammatory hepcidin by reducing IL-6 secretion and promoting SIRT1-mediated STAT3 deacetylation\u003c\/a\u003e;\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29147463\"\u003eAcidic Polysaccharide from Angelica sinensis Reverses Anemia of Chronic Disease Involving the Suppression of Inflammatory Hepcidin and NF-κB Activation\u003c\/a\u003e;\u003ca href=\"https:\/\/doi.org\/10.1186\/s12950-017-0166-3\"\u003eEvaluation of a competitive hepcidin ELISA assay in the differential diagnosis of iron deficiency anaemia with concurrent inflammation and anaemia of inflammation in elderly patients\u003c\/a\u003e;\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27923278\"\u003eAMPK serves as a Therapeutic Target against Anemia of Inflammation\u003c\/a\u003e;\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28405918\"\u003eHepcidin suppression in β‑thalassemia is associated with the down‑regulation of atonal homolog 8\u003c\/a\u003e;\u003ca href=\"https:\/\/doi.org\/10.1016\/j.tube.2017.11.011\"\u003eModulation of iron status biomarkers in tuberculosis-diabetes co-morbidity\u003c\/a\u003e;\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28584599\"\u003eThe Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus.\u003c\/a\u003e;\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29909502\"\u003eIncreased NGAL level associated with iron store in chronic kidney disease with anemia\u003c\/a\u003e;\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29318945\"\u003eRelationship between obesity and iron deficiency anemia: is there a role of hepcidin?\u003c\/a\u003e;\u003ca href=\"http:\/\/www.seer.ufrgs.br\/hcpa\/article\/view\/77856\"\u003eHepcidin serum levels in HCV chronically mono-infected naïve patients, compared to healthy individuals\u003c\/a\u003e;\u003c\/p\u003e","brand":"ABCbiolab","offers":[{"title":"96T \/ The minimum detectable dose of this kit is typically less than 112pg\/mL \/ Homo sapiens (Human)","offer_id":42481750114538,"sku":"ABCC24941","price":665.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/products\/74120318_padded_logo_83f8ca77-b634-4484-9825-919ec0bcf328.png?v=1644865877","url":"https:\/\/danabiosci.com\/products\/elisa-kit-for-hepcidin-hepc-abcc24941","provider":"Dana Bioscience","version":"1.0","type":"link"}