{"product_id":"ea345","title":"MEK3 Rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e IHC\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human, Mouse, Rat\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e IHC 1:100-200\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 34,39kDa\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 5606\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P46734\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Cytosol,Nucleus\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e MAP2K3; MKK3; PRKMK3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK3; MAPK\/ERK kinase 3\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e Three alternatively spliced transcript variants of MEK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MEK3b is the predominant form of MEK3 and strongly activates p38 MAP kinase .","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50411008852248,"sku":"EA345","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EA345-c-1.jpg?v=1751068590","url":"https:\/\/danabiosci.com\/products\/ea345","provider":"Dana Bioscience","version":"1.0","type":"link"}