{"product_id":"ea230","title":"α-actinin Rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB, IHC\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Rat, Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1:1,000-2,000    IHC 1:200-500\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 103kDa\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 87\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P12814\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e actinin 1 smooth muscle antibody, actinin alpha 1 antibody, ACTN 1 antibody, FLJ40884 antibody\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50410992664856,"sku":"EA230","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EA230-c-1.jpg?v=1751068178","url":"https:\/\/danabiosci.com\/products\/ea230","provider":"Dana Bioscience","version":"1.0","type":"link"}