{"product_id":"ea041","title":"Lamin B1 Rabbit pAb","description":"\u003cstrong\u003eApplications:\u003c\/strong\u003e WB, IHC\u003cbr\u003e\u003cstrong\u003eReactivity:\u003c\/strong\u003e Human, Rat, Mouse\u003cbr\u003e\u003cstrong\u003eSource:\u003c\/strong\u003e Rabbit\u003cbr\u003e\u003cstrong\u003eDilution:\u003c\/strong\u003e WB 1:1,000-3,000  IHC: 1:500-1,000\u003cbr\u003e\u003cstrong\u003eImmunogen:\u003c\/strong\u003e Recombinant Protein\u003cbr\u003e\u003cstrong\u003eStorage_stability:\u003c\/strong\u003e PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.\u003cbr\u003e\u003cstrong\u003eClonality:\u003c\/strong\u003e Polyclonal\u003cbr\u003e\u003cstrong\u003eIsotype:\u003c\/strong\u003e IgG\u003cbr\u003e\u003cstrong\u003eConcentration:\u003c\/strong\u003e 1mg\/mL\u003cbr\u003e\u003cstrong\u003eObserved_band(KD):\u003c\/strong\u003e 68,45kDa\u003cbr\u003e\u003cstrong\u003eHuman_gene_id:\u003c\/strong\u003e 4001\u003cbr\u003e\u003cstrong\u003eHuman_swiss_prot_no:\u003c\/strong\u003e P20700\u003cbr\u003e\u003cstrong\u003eSubcellular_location:\u003c\/strong\u003e Mitochondrion inner membrane\u003cbr\u003e\u003cstrong\u003eOther_name:\u003c\/strong\u003e ADLD, LMB1,LMNB1, MGC111419, OTTHUMP00000159218\u003cbr\u003e\u003cstrong\u003eBackground:\u003c\/strong\u003e The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.","brand":"ELK Biotechnology","offers":[{"title":"50μL","offer_id":50410972872984,"sku":"EA041","price":250.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0590\/5652\/1400\/files\/EA041-c-1.jpg?v=1751067807","url":"https:\/\/danabiosci.com\/products\/ea041","provider":"Dana Bioscience","version":"1.0","type":"link"}